Right here are the 55 US AI startups that raised $100M or more in 2025

The AI industry entered 2025 with solid momentum. 

There had been 49 startups that raised funding rounds value $100 million or more in 2024, per our count at TechCrunch; three corporations raised a couple of “mega-spherical,” and 7 corporations raised rounds that had been $1 billion in size or better. 

The industry didn’t unhurried down in 2025. Whereas much less corporations raised rounds better than $1 billion, four — Anthropic raised two rounds over $1 billion — vastly more corporations raised more than one rounds in comparison to 2024, eight.  

How will 2026 overview? Elon Musk’s xAI announced a $20 billion Series E spherical and Sam Altman’s mind laptop interface startup Merge Labs raised a $250 million seed spherical (with OpenAI as the lead investor) in the first few weeks of 2026, so indicators explain yet every other solid year. In spite of the entirety, it’s peaceable early; we’ll be watching to peek if the momentum continues. 

Right here are the total U.S. AI corporations that raised $100 million closing year: 

December: 

• Austin, Texas-essentially based Mythic, which builds vitality-efficient compute for AI, raised a $125 million enterprise spherical that changed into once led by DCVC. The spherical changed into once announced on December 17 and integrated SoftBank, NEA and Linse Capital, among other investors.  

• Chai Discovery announced a $130 million Series B spherical on December 15. The spherical valued the firm that builds AI models for biotech and drug discovery at $1.2 billion. Oak HC/FT and Overall Catalyst co-led the spherical.  

• Generative media platform Fal announced its third funding spherical of 2025 on December 9. This $140 million Series D spherical changed into once led by Sequoia and valued the firm at more than $4.5 billion.  

• Unconventional AI announced a monster $475 million seed spherical led by Lightspeed Challenge Partners and Andreesen Horowitz on December 8. The spherical valued the one-year-former startup, which is rethinking the basis of computers within the age of AI, at with regards to $4.5 billion.  

• Boston-essentially based 7AI, which builds cybersecurity AI agents, raised a $130 million Series A spherical that changed into once announced on December 4. Index Ventures led the spherical with participation from Greylock, Spark Capital and CRV, among others.  

November

• All-in-one AI workspace platform Genspark announced a $275 million Series B spherical that valued the firm at $1.25 billion on November 20. The spherical integrated Emergence Capital Partners, SBI Funding, and LG Technology Ventures, among others.  

• Luma AI, which builds models faded for checklist and video introduction, raised $900 million in a Series C spherical that valued the startup at $4 billion. The spherical changed into once led by Humain with participation from Andreessen Horowitz, AMD Ventures and Amplify Partners, among others.  

• Anysphere, the maker of viral vibe-coding platform Cursor, raised $2.3 billion in a funding spherical that valued the firm at $29.3 billion. The spherical changed into once announced on November 13 and is the firm’s 2d funding spherical this year.  

• Parallel, which builds web infrastructure for AI agents, raised a $100 million Series A spherical that changed into once announced on November 12. The spherical changed into once co-led by Index Ventures and Kleiner Perkins.  

• Healthcare AI agent startup Hippocratic AI raised a $126 million Series C spherical that valued the firm at $3.5 billion. The spherical changed into once the firm’s 2d this year, changed into once announced on November 3, and changed into once led by Avenir Boost.  

October

• Fireworks AI, a platform that permits customers to invent AI capabilities using start source models, raised a $250 million Series C spherical that changed into once announced on October 28. The spherical valued the firm at $4 billion.  

• Challenge AI startup Uniphore is valued at $2.5 billion after a $260 million Series F spherical that changed into once announced on October 22. The spherical integrated Snowflake Ventures, Nvidia, Databricks Ventures, and AMD, among others.  

• Sesame, a articulate AI firm, raised a $250 million Series B spherical co-led by Sequoia and Spark Capital. The spherical changed into once announced on October 21 and furthermore integrated SignalRank as a participant.  

• Cambridge, Massachusetts’s essentially based OpenEvidence, which builds an AI chatbot for the clinical field, raised its 2d funding spherical of 2025. The $200 million Series C spherical changed into once announced on October 20 and valued the firm at $6 billion.  

• Lila Sciences, which is taking a peek to invent a science superintelligence platform, announced its 2d funding spherical of 2025 on October 14. The $350 million Series A spherical changed into once co-led by Braidwell and Collective Global. 

• DeepSeek competitor Reflection AI announced its 2d mega-spherical of the year on October 9. The $2 billion Series B spherical valued the firm at $8 billion and changed into once led by Nvidia.  

• EvenUp, which builds AI for the private break prison field, announced a $150 million Series E spherical that valued the firm at more $2 billion on October 7. The spherical changed into once led by Bessemer with participation from Lightspeed, Bain Capital and SignalFire, among others.  

September

• Periodic Labs, which is constructing an AI scientist, announced a $300 million seed spherical on September 30. Felicis and Andreessen Horowitz led the spherical with participation from Nvidia, Lightspeed, and Khosla Ventures, among others.  

• Cerebras Programs, an AI infrastructure firm, raised a unparalleled $1.1 billion Series G spherical that valued the firm at $8.1 billion. The spherical changed into once announced on September 30 and changed into once co-led by Fidelity and Atreides Administration. 

• Modular announced a $250 million funding spherical on September 24. The spherical changed into once led by US Modern Technology Fund with participation from GV, Greylock, and Overall Catalyst, among others.  

• Distyl AI, which builds AI enterprise tool, raised a $175 million Series B spherical that changed into once announced on September 23. This spherical valued the startup at $1.8 billion and integrated investors care for Khosla Ventures and Lightspeed.  

• AI infrastructure startup Upscale AI raised a unparalleled $100 million seed spherical that changed into once co-led by Maverick Silicon and Mayfield. The spherical changed into once announced on September 17 and furthermore integrated StepStone Neighborhood, Stanford College, and Qualcomm Ventures, among others.  

• Groq, an AI inference firm, raised a $750 million Series D-3 spherical that valued the firm at with regards to $6.9 billion. The spherical changed into once announced on September 17 and changed into once led by Disruptive.  

• AI coaching startup Invisible Applied sciences changed into once valued at $2 billion after a $100 million fundraise that changed into once announced on September 16. The elevate changed into once led by Vanara Capital with participation from Greycroft, Tallwoods Capital, and Freestyle Capital, among others.  

• Cognition AI, the creator of vibe-coding agent Devin, raised a $400 million Series C spherical that changed into once announced on September 8. The spherical changed into once led by Founders Fund and valued the firm at $10.2 billion. 

• AI Infrastructure startup Baseten raised a $150 million Series D spherical that valued the firm at $2.1 billion. The September 5 spherical changed into once led by Bond with participation from CapitalG, IVP and Spark Capital, among others.  

• Bret Taylor’s customer support AI agent platform Sierra raised $350 million in a spherical led by Greenoaks Capital. This fundraise changed into once announced on September 4 and valued Sierra at more than $10 billion.  

• You.com, a personalized AI search engine, raised a $100 million Series C spherical led by Cox Enterprises. The spherical changed into once announced on September 3 and valued the firm at $1.5 billion.  

• AI analysis lab Anthropic raised its 2d spherical of 2025 in September. Anthropic announced a $13 billion Series F spherical on September 2 that valued the firm at $183 billion. The spherical changed into once led by Iconiq, Fidelity, and Lightspeed.  

August

• Healthcare and housing automation platform EliseAI raised $250 million in a Series E spherical that valued the startup at $2.2 billion. The spherical, which changed into once announced on August 20, changed into once led by Andreessen Horowitz.
• Decart, an AI analysis lab, raised $100 million at a $3.1 billion valuation. The spherical integrated Sequoia Capital, Benchmark, and Zeev Ventures, among others, and changed into once announced on August 7.

July

• Generative media platform Fal raised a $125 million Series C spherical led by Meritech Capital Partners. The firm announced the spherical, which values Fal at $1.5 billion, on July 31. Salesforce Ventures, Shopify Ventures, Google AI Futures Fund, and others joined the spherical.
• 5-year-former Ambience Healthcare, which is constructing an AI healthcare operating blueprint, raised a $243 million Series C spherical that changed into once led by Oak HC/FT and Andreessen Horowitz. Kleiner Perkins, OpenAI Startup Fund, Smash Capital, and others furthermore participated within the spherical.
• Reka AI, an AI analysis lab, raised $110 million in a spherical that integrated Snowflake and Nvidia. The Series B spherical changed into once announced on July 22 and values the firm at $1 billion.
• AI analysis lab Pondering Machines Lab confirmed that it raised $2 billion on July 15. This unparalleled seed spherical changed into once led by Andreessen Horowitz with participation from Nvidia, Accel, and AMD, among others. The spherical values the firm at $12 billion.
• Cambridge, Massachusetts-essentially based OpenEvidence, which is constructing an AI-powered search instrument for clinicians, raised $210 million at a $3.5 billion valuation. The Series B spherical changed into once announced on July 15 and changed into once led by Kleiner Perkins and GV.
• Harmonic, which is constructing a mathematical reasoning engine, raised a $100 million Series B spherical led by Kleiner Perkins. The spherical changed into once announced on July 10 and values the firm at $875 million.

June

• Healthcare AI unicorn Abridge announced it raised a $300 million Series E spherical that values the firm at $5.3 billion. The spherical changed into once led by Andreessen Horowitz with Khosla Ventures collaborating. It changed into once the firm’s 2d spherical of 2025.
• Harvey, which builds AI tools for the prison industry, announced it raised its 2d $300 million spherical of 2025 on June 23. This most recent Series E spherical changed into once co-led by Kleiner Perkins and Coatue and brings the firm’s valuation to $5 billion.
• Healthcare AI startup Tennr announced it raised a $101 million Series C spherical led by IVP with participation from Lightspeed Challenge Partners, GV, and Andreessen Horowitz, among others. The spherical values the firm at $605 million.
• Challenge search startup Procure continues to rake in cash. The firm announced a $150 million Series F spherical on June 10, led by Wellington Administration with participation from Sequoia, Lightspeed Challenge Partners, and Kleiner Perkins, among others. Procure is now valued at $7.25 billion.
• Anysphere, the AI analysis lab within the back of AI coding instrument Cursor, raised a unparalleled $900 million Series C spherical that values the firm at with regards to $10 billion. The spherical changed into once led by Thrive Capital with participation from Andreessen Horowitz, Accel, and DST Global.

May per chance per chance perchance perchance

• AI info labeling startup Snorkel AI announced a $100 million Series D spherical on May per chance per chance perchance perchance 29, valuing the firm at $1.3 billion. The spherical changed into once led by Addition with participation from Prosperity7 Ventures, Lightspeed Challenge Partners, and Greylock.
• LMArena, a most in vogue, neighborhood-driven benchmarking instrument for AI models, raised a $100 million seed spherical that valued the startup at $600 million. The spherical changed into once announced on May per chance per chance perchance perchance 21 and changed into once co-led by Andreessen Horowitz and UC Investments. Lightspeed Challenge Partners, Kleiner Perkins, and Felicis furthermore participated, among others.
• Las Vegas-essentially based AI infrastructure firm TensorWave announced a $100 million Series A spherical on May per chance per chance perchance perchance 14. The spherical changed into once co-led by Magnetar Capital and AMD Ventures with participation from Prosperity7 Ventures, Nexus Challenge Partners, and Maverick Silicon.

April

• SandboxAQ closed a $450 million Series E spherical on April 4 that valued the AI mannequin firm at $5.7 billion. The spherical integrated Nvidia, Google, and Bridgewater Pals founder Ray Dalio among other investors.
• Runway, which creates AI models for media production, raised a $308 million Series D spherical that changed into once announced on April 3, valuing the firm at $3 billion. It changed into once led by Overall Atlantic. SoftBank, Nvidia, and Fidelity furthermore participated.

March

• AI behemoth OpenAI raised a document-breaking $40 billion funding spherical that valued the startup at $300 billion. This spherical, which closed on March 31, changed into once led by SoftBank with participation from Thrive Capital, Microsoft, and Coatue, among others.
• On March 25, Nexthop AI, an AI infrastructure firm, announced that it had raised a Series A spherical led by Lightspeed Challenge Partners. The $110 million spherical furthermore integrated Kleiner Perkins, Battery Ventures, and Emergent Ventures, among others.
• Cambridge Massachusetts-essentially based Insilico Medicines raised $110 million for its generative AI-powered drug discovery platform as announced on March 13. This Series E spherical valued the firm at $1 billion and changed into once co-led by Impress Partners and Pudong Chuangtou.
• AI infrastructure firm Celestial AI raised a $250 million Series C spherical that valued the firm at $2.5 billion. The March 11 spherical changed into once led by Fidelity with participation from Tiger Global, BlackRock, and Intel CEO Lip-Bu Tan, among others.
• Lila Sciences raised a $200 million seed spherical because it looks to plot a science superintelligence platform. The spherical changed into once led by Flagship Pioneering. The Cambridge, Massachusetts-essentially based firm furthermore got funding from March Capital, Overall Catalyst, and ARK Challenge Fund, among others.
• Brooklyn-essentially based Reflection.Ai, which looks to invent superintelligent self enough systems, raised a $130 million Series A spherical that values the 1-year-former firm at $580 million. The spherical changed into once led by Lightspeed Challenge Partners and CRV.
• AI coding startup Turing closed a Series E spherical on March 7 that valued the startup, which partners with LLM corporations, at $2.2 billion. The $111 million spherical changed into once led by Khazanah Nasional with participation from WestBridge Capital, Gaingels, and Sozo Ventures, among others.
• Defend AI, an AI defense tech startup, raised $240 million in a Series F spherical that closed on March 6. This spherical changed into once co-led by L3Harris Applied sciences and Hanwha Aerospace, with participation from Andreessen Horowitz and the US Modern Technology Fund, among others. The spherical valued the firm at $5.3 billion
• AI analysis and immense language mannequin firm Anthropic raised $3.5 billion in a Series E spherical that valued the startup at $61.5 billion. The spherical changed into once announced on March 3 and changed into once led by Lightspeed with participation from Salesforce Ventures, Menlo Ventures, and Overall Catalyst, among others.

February

• Together AI, which creates start source generative AI and AI mannequin snort infrastructure, raised a $305 million Series B spherical that valued the firm at $3.3 billion. The February 20 spherical changed into once co-led by Prosperity7 and Overall Catalyst with participation from Salesforce Ventures, Nvidia, Lux Capital, and others.
• AI infrastructure firm Lambda raised a $480 million Series D spherical that changed into once announced on February 19. The spherical valued the startup at with regards to $2.5 billion and changed into once co-led by SGW and Andra Capital. Nvidia, G Squared, ARK Make investments, and others furthermore participated.
• Abridge, an AI platform that transcribes affected person-clinician conversations, changed into once valued at $2.75 billion in a Series D spherical that changed into once announced on February 17. The $250 million spherical changed into once co-led by IVP and Elad Gil. Lightspeed, Redpoint, and Spark Capital furthermore participated, among others.
• Eudia, an AI prison tech firm, raised $105 million in a Series A spherical led by Overall Catalyst. Floodgate, Defy Ventures, and All over the assign the assign Ventures furthermore participated within the spherical as well to other VC corporations and a immense likelihood of angel investors. The spherical closed on February 13.
• AI hardware startup EnCharge AI raised a $100 million Series B spherical that furthermore closed on February 13. The spherical changed into once led by Tiger Global with participation from Scout Ventures, Samsung Ventures, and RTX Ventures, among others. The Santa Clara-essentially based swap changed into once based in 2022.
• AI prison tech firm Harvey raised a $300 million Series D spherical that valued the three-year-former firm at $3 billion. The spherical changed into once led by Sequoia and announced on February 12. OpenAI Startup Fund, Kleiner Perkins, Elad Gil, and others furthermore participated within the elevate.

January

• Synthetic articulate startup ElevenLabs raised a $180 million Series C spherical that valued the firm at more than $3 billion. It changed into once announced on January 30. The spherical changed into once co-led by Iconiq and Andreessen Horowitz. Sequoia, NEA, Salesforce Ventures, and others furthermore participated within the spherical.
• Hippocratic AI, which develops immense language models for the healthcare industry, announced a $141 million Series B spherical on January 9. This spherical valued the firm at more than $1.6 billion and changed into once led by Kleiner Perkins. Andreessen Horowitz, Nvidia, and Overall Catalyst furthermore participated, among others.

This fragment changed into once up thus some distance on April 23, June 18, August 27, November 26 and January 19, 2026 to include more affords.

This fragment has been up thus some distance to grab away that Abridge depends in Pittsburgh; the firm changed into once based there.

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